Vincent Timmerman Selected Research

Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)

1/2023	The chaperone-assisted selective autophagy complex dynamics and dysfunctions.
1/2019	Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies.
11/2016	Molecular Chaperones in the Pathogenesis of Amyotrophic Lateral Sclerosis: The Role of HSPB1.
4/2016	Mitochondria-associated membranes as hubs for neurodegeneration.
6/2004	DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4).

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Vincent Timmerman Research Topics

Disease

14	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 11/2022 - 06/2002
11	Hereditary Sensory and Autonomic Neuropathies (HSAN) 12/2023 - 10/2002
9	Peripheral Nervous System Diseases (PNS Diseases) 01/2023 - 03/2002
9	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 06/2004
5	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2023 - 06/2004
3	Type 2I Charcot-Marie-Tooth disease 01/2023 - 08/2010
3	Epilepsy (Aura) 12/2019 - 09/2007
3	Type 2F Charcot-Marie-Tooth disease 01/2016 - 06/2004
3	Infections 08/2015 - 03/2003
2	Type II Distal Hereditary Motor Neuropathy 01/2023 - 06/2004
2	Neoplasms (Cancer) 01/2023 - 01/2016
2	Disease Progression 11/2022 - 04/2009
2	Pain (Aches) 01/2022 - 11/2013
2	Inflammation (Inflammations) 11/2020 - 01/2019
2	Distal Myopathies (Distal Muscular Dystrophy) 01/2020 - 01/2018
2	Brain Diseases (Brain Disorder) 12/2019 - 11/2015
2	Occipital horn syndrome 10/2019 - 03/2010
2	Menkes Kinky Hair Syndrome (Menkes Disease) 10/2019 - 03/2010
2	Parkinson Disease (Parkinson's Disease) 04/2016 - 01/2010
2	Type 2B Charcot-Marie-Tooth disease 05/2014 - 03/2003
2	Necrosis 07/2010 - 04/2009
2	Reinfection 04/2009 - 03/2003
2	Congenital Generalized Lipodystrophy (Berardinelli-Seip Congenital Lipodystrophy) 05/2008 - 03/2004
2	Demyelinating Diseases (Demyelinating Disease) 07/2007 - 08/2005
2	Hereditary Sensory and Motor Neuropathy (Dejerine Sottas Disease) 08/2005 - 06/2002
2	Foot Ulcer 03/2003 - 03/2003
1	Neuroblastoma 01/2023
1	Type 2D Charcot-Marie-Tooth disease 11/2022
1	Chronic Pain 01/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2021
1	Neuroinflammatory Diseases 11/2020
1	Huntington Disease (Huntington's Disease) 01/2020
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2020
1	Microcephaly 12/2019

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 01/2023 - 11/2002
10	Small Heat-Shock ProteinsIBA 01/2020 - 06/2004
6	Serine C-PalmitoyltransferaseIBA 01/2019 - 10/2002
4	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2023 - 06/2004
4	Phosphotransferases (Kinase)IBA 01/2023 - 04/2009
3	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2023 - 01/2019
3	polyglutamineIBA 01/2023 - 01/2018
3	SphingolipidsIBA 01/2019 - 10/2010
3	Dynamin IIIBA 07/2009 - 03/2005
2	Nerve Growth Factor (NGF)IBA 12/2023 - 04/2009
2	Transfer RNA (tRNA)IBA 01/2023 - 08/2014
2	Ligases (Synthetase)IBA 01/2023 - 08/2014
2	Proline (L-Proline)FDA Link 01/2023 - 01/2020
2	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2023 - 01/2023
2	UbiquitinIBA 01/2023 - 01/2019
2	InflammasomesIBA 11/2020 - 08/2015
2	alpha-Crystallins (alpha-Crystallin)IBA 01/2019 - 08/2010
2	DNA (Deoxyribonucleic Acid)IBA 05/2012 - 06/2004
2	EnzymesIBA 06/2011 - 10/2010
2	Myelin ProteinsIBA 06/2010 - 04/2005
1	tryptophyltryptophanIBA 01/2023
1	tributyl phosphate (TBP)IBA 01/2023
1	trans-sodium crocetinate (crocetin)IBA 01/2023
1	Kelch-Like ECH-Associated Protein 1IBA 01/2023
1	Superoxide Dismutase-1IBA 01/2023
1	Histone Deacetylase 6IBA 01/2023
1	AngiomotinsIBA 01/2023
1	Transcriptional Coactivator with PDZ-Binding Motif ProteinsIBA 01/2023
1	NF-kappaB-Inducing KinaseIBA 01/2023
1	ActininIBA 01/2023
1	CalciumIBA 01/2023
1	Carrier Proteins (Binding Protein)IBA 01/2023
1	Crystallins (Crystallin)IBA 01/2023
1	gamma-Aminobutyric Acid (GABA)IBA 01/2023
1	Isoleucine (L-Isoleucine)FDA Link 01/2023
1	Peptide Initiation Factors (Initiation Factor)IBA 01/2023
1	Transcription Factors (Transcription Factor)IBA 01/2023
1	TubulinIBA 01/2023
1	Tyrosine-tRNA LigaseIBA 01/2023
1	Valine (L-Valine)FDA Link 01/2023
1	NF-kappa B (NF-kB)IBA 01/2023
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2023
1	MyogeninIBA 01/2023
1	Myosin Heavy Chains (Myosin Heavy Chain)IBA 01/2023
1	Sirolimus (Rapamycin)FDA Link 01/2023
1	TATA-Box Binding Protein (TATA-Binding Protein)IBA 01/2023
1	Prokaryotic Initiation Factor-2IBA 01/2023
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2023
1	Basic-Leucine Zipper Transcription FactorsIBA 01/2023
1	Actin-Related Protein 2IBA 01/2023
1	Lysosomal Membrane ProteinsIBA 01/2023
1	Phospholipase C gammaIBA 01/2023
1	Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA 11/2022
1	Biomarkers (Surrogate Marker)IBA 11/2022
1	Analgesics (Analgesic Drugs)IBA 01/2022
1	Codon (Codons)IBA 01/2020
1	Valine-tRNA LigaseIBA 12/2019
1	Copper-Transporting ATPasesIBA 10/2019
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2019
1	Antiviral Agents (Antivirals)IBA 01/2019
1	AntigensIBA 01/2019
1	Green Fluorescent ProteinsIBA 01/2019
1	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 01/2019

Therapy/Procedure

3	Therapeutics 01/2022 - 01/2006
2	Surgical Amputation (Amputations) 03/2003 - 03/2003
1	Denervation 11/2022